What is Onfi?
Onfi (clobazam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Clobazam affects chemicals in the brain that may be unbalanced in people with anxiety.
Onfi is used in combination with other medications to treat seizures caused by Lennox-Gastaut syndrome, a severe form of childhood epilepsy that also causes developmental and behavior problems.
Onfi may also be used for purposes not listed in this medication guide.
You should not use Onfi if you are allergic to clobazam.
You may have thoughts about suicide while taking this medication. Your doctor will need to check you at regular visits.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Before taking this medicine
You should not take Onfi if you are allergic to clobazam.
To make sure you can safely take Onfi, tell your doctor if you have:
liver or kidney disease;
any type of breathing problem or lung disease;
a history of depression or suicidal thoughts or behavior;
a history of drug or alcohol addiction; or
if you use a narcotic (opioid) medication.
Some young people have thoughts about suicide when first taking Onfi. Your doctor will need to check your progress at regular visits while you are using this medicine. Your family or other caregivers should also be alert to changes in your mood or symptoms.
It is not known whether Onfi will harm an unborn baby. Clobazam may cause breathing problems, feeding problems, and low body temperature in a newborn. Your baby could also become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant. Use effective birth control to prevent pregnancy while you are taking Onfi.
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